Peer-Reviewed Academic Journal
Continental Journal of Applied Sciences
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ADVANCES IN THE TECHNOLOGY OF TASTE- MASKING OF UNPLEASANT TASTING ORAL DOSAGE FORMS: A REVIEW

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Abstract

Most of the pharmaceuticals are administered by the popular route of drug delivery, the oral route. Taste is an important and critical parameter in administering formulations which comes in contact with the taste buds. Many drugs have bitter taste, thus this is one of the important formulation problem encountered. Bitter taste of drugs has posed a constant problem in the treatment of patients due to their inability or unwillingness to swallow such formulation especially in children and elderly. Thus masking of unpleasant taste characteristics of drug is an important factor in formulation of these agents. This lead to the development of taste masking technologies which improved the characteristics of the dosage form and good patient compliance is achieved. This review describes the trend in taste masking technologies by studying various methodologies for masking the obnoxious taste of drugs, some of which includes Taste-masking by Granulation, Ion Exchange Resins, Sweeteners and flavorants, Microencapsulation, Formulation of Inclusion Complexes, adsorption, Prodrug Approach, Gelation, Solid Dispersion System, Development of Liposome, Multiple Emulsions. The recent techniques which include the use of bitter taste blockers which specifically block the bitter taste but not the pleasant taste of any additive as well as taste masking nanotechnology using nanolipidic particles were also discussed.

Keywords

#Taste masking #dosage form #palatability #and polymer
Publication Date May 21, 2026
Digital Object Identifier (DOI) Registered
Journal Volume & Issue Vol 10